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svgp12 (normal human glial cell line)  (BioResource International Inc)

 
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    BioResource International Inc svgp12 (normal human glial cell line)
    Effects of water (CF-WE) and methanol (CF-ME) extracts of Cimicifuga foetida on the viability of glioblastoma (GBM) and glial cells. ( A ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with varying concentrations (0–800 μg/mL) of CF-WE for 24, 48, and 72 h showed a significant dose- and time-dependent decrease in cell viability, with stronger effects at higher concentrations and longer treatment durations. ( B ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with CF-ME (0–150 μg/mL) for the same durations exhibited a stronger inhibitory effect, also in a dose- and time-dependent manner. ( C ) Cell viability of human normal glial cell line <t>SVGp12</t> treated with CF-WE (left) and CF-ME (right) under similar conditions showed reduced cell viability, but SVGp12 cells exhibited higher overall viability and IC 50 values than GBM cells, indicating lower toxicity toward normal glial cells. * Asterisks indicate statistical significance compared to control (0 μg/mL) ( p < 0.05). Error bars represent the mean ± SD of three independent experiments.
    Svgp12 (Normal Human Glial Cell Line), supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/svgp12 (normal human glial cell line)/product/BioResource International Inc
    Average 90 stars, based on 1 article reviews
    svgp12 (normal human glial cell line) - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Methanolic Extract of Cimicifuga foetida Induces G 1 Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells"

    Article Title: Methanolic Extract of Cimicifuga foetida Induces G 1 Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells

    Journal: Nutrients

    doi: 10.3390/nu16193254

    Effects of water (CF-WE) and methanol (CF-ME) extracts of Cimicifuga foetida on the viability of glioblastoma (GBM) and glial cells. ( A ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with varying concentrations (0–800 μg/mL) of CF-WE for 24, 48, and 72 h showed a significant dose- and time-dependent decrease in cell viability, with stronger effects at higher concentrations and longer treatment durations. ( B ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with CF-ME (0–150 μg/mL) for the same durations exhibited a stronger inhibitory effect, also in a dose- and time-dependent manner. ( C ) Cell viability of human normal glial cell line SVGp12 treated with CF-WE (left) and CF-ME (right) under similar conditions showed reduced cell viability, but SVGp12 cells exhibited higher overall viability and IC 50 values than GBM cells, indicating lower toxicity toward normal glial cells. * Asterisks indicate statistical significance compared to control (0 μg/mL) ( p < 0.05). Error bars represent the mean ± SD of three independent experiments.
    Figure Legend Snippet: Effects of water (CF-WE) and methanol (CF-ME) extracts of Cimicifuga foetida on the viability of glioblastoma (GBM) and glial cells. ( A ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with varying concentrations (0–800 μg/mL) of CF-WE for 24, 48, and 72 h showed a significant dose- and time-dependent decrease in cell viability, with stronger effects at higher concentrations and longer treatment durations. ( B ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with CF-ME (0–150 μg/mL) for the same durations exhibited a stronger inhibitory effect, also in a dose- and time-dependent manner. ( C ) Cell viability of human normal glial cell line SVGp12 treated with CF-WE (left) and CF-ME (right) under similar conditions showed reduced cell viability, but SVGp12 cells exhibited higher overall viability and IC 50 values than GBM cells, indicating lower toxicity toward normal glial cells. * Asterisks indicate statistical significance compared to control (0 μg/mL) ( p < 0.05). Error bars represent the mean ± SD of three independent experiments.

    Techniques Used: Control

    IC 50 values of malignant glioma cells and normal glial cells after treatment with extract of Cimicifuga foetida . U87 MG, A172, T98G, and SVGp12 cells were treated with different doses of CF-WE and CF-ME for 72 h, respectively. Cell viability was detected using an MTT assay with an ELISA reader to measure absorbance values. IC 50 values were calculated after plotting the regression lines. Data are presented as means ± standard deviation.
    Figure Legend Snippet: IC 50 values of malignant glioma cells and normal glial cells after treatment with extract of Cimicifuga foetida . U87 MG, A172, T98G, and SVGp12 cells were treated with different doses of CF-WE and CF-ME for 72 h, respectively. Cell viability was detected using an MTT assay with an ELISA reader to measure absorbance values. IC 50 values were calculated after plotting the regression lines. Data are presented as means ± standard deviation.

    Techniques Used: MTT Assay, Enzyme-linked Immunosorbent Assay



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    BioResource International Inc svgp12 (normal human glial cell line)
    Effects of water (CF-WE) and methanol (CF-ME) extracts of Cimicifuga foetida on the viability of glioblastoma (GBM) and glial cells. ( A ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with varying concentrations (0–800 μg/mL) of CF-WE for 24, 48, and 72 h showed a significant dose- and time-dependent decrease in cell viability, with stronger effects at higher concentrations and longer treatment durations. ( B ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with CF-ME (0–150 μg/mL) for the same durations exhibited a stronger inhibitory effect, also in a dose- and time-dependent manner. ( C ) Cell viability of human normal glial cell line <t>SVGp12</t> treated with CF-WE (left) and CF-ME (right) under similar conditions showed reduced cell viability, but SVGp12 cells exhibited higher overall viability and IC 50 values than GBM cells, indicating lower toxicity toward normal glial cells. * Asterisks indicate statistical significance compared to control (0 μg/mL) ( p < 0.05). Error bars represent the mean ± SD of three independent experiments.
    Svgp12 (Normal Human Glial Cell Line), supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/svgp12 (normal human glial cell line)/product/BioResource International Inc
    Average 90 stars, based on 1 article reviews
    svgp12 (normal human glial cell line) - by Bioz Stars, 2026-03
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    Image Search Results


    Effects of water (CF-WE) and methanol (CF-ME) extracts of Cimicifuga foetida on the viability of glioblastoma (GBM) and glial cells. ( A ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with varying concentrations (0–800 μg/mL) of CF-WE for 24, 48, and 72 h showed a significant dose- and time-dependent decrease in cell viability, with stronger effects at higher concentrations and longer treatment durations. ( B ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with CF-ME (0–150 μg/mL) for the same durations exhibited a stronger inhibitory effect, also in a dose- and time-dependent manner. ( C ) Cell viability of human normal glial cell line SVGp12 treated with CF-WE (left) and CF-ME (right) under similar conditions showed reduced cell viability, but SVGp12 cells exhibited higher overall viability and IC 50 values than GBM cells, indicating lower toxicity toward normal glial cells. * Asterisks indicate statistical significance compared to control (0 μg/mL) ( p < 0.05). Error bars represent the mean ± SD of three independent experiments.

    Journal: Nutrients

    Article Title: Methanolic Extract of Cimicifuga foetida Induces G 1 Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells

    doi: 10.3390/nu16193254

    Figure Lengend Snippet: Effects of water (CF-WE) and methanol (CF-ME) extracts of Cimicifuga foetida on the viability of glioblastoma (GBM) and glial cells. ( A ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with varying concentrations (0–800 μg/mL) of CF-WE for 24, 48, and 72 h showed a significant dose- and time-dependent decrease in cell viability, with stronger effects at higher concentrations and longer treatment durations. ( B ) Cell viability of U87 MG, A172, and T98G GBM cell lines treated with CF-ME (0–150 μg/mL) for the same durations exhibited a stronger inhibitory effect, also in a dose- and time-dependent manner. ( C ) Cell viability of human normal glial cell line SVGp12 treated with CF-WE (left) and CF-ME (right) under similar conditions showed reduced cell viability, but SVGp12 cells exhibited higher overall viability and IC 50 values than GBM cells, indicating lower toxicity toward normal glial cells. * Asterisks indicate statistical significance compared to control (0 μg/mL) ( p < 0.05). Error bars represent the mean ± SD of three independent experiments.

    Article Snippet: U87 MG, A172, and T98G (GBM cell lines) and SVGp12 (normal human glial cell line) were obtained from the Bioresource Collection and Research Center (BCRC).

    Techniques: Control

    IC 50 values of malignant glioma cells and normal glial cells after treatment with extract of Cimicifuga foetida . U87 MG, A172, T98G, and SVGp12 cells were treated with different doses of CF-WE and CF-ME for 72 h, respectively. Cell viability was detected using an MTT assay with an ELISA reader to measure absorbance values. IC 50 values were calculated after plotting the regression lines. Data are presented as means ± standard deviation.

    Journal: Nutrients

    Article Title: Methanolic Extract of Cimicifuga foetida Induces G 1 Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells

    doi: 10.3390/nu16193254

    Figure Lengend Snippet: IC 50 values of malignant glioma cells and normal glial cells after treatment with extract of Cimicifuga foetida . U87 MG, A172, T98G, and SVGp12 cells were treated with different doses of CF-WE and CF-ME for 72 h, respectively. Cell viability was detected using an MTT assay with an ELISA reader to measure absorbance values. IC 50 values were calculated after plotting the regression lines. Data are presented as means ± standard deviation.

    Article Snippet: U87 MG, A172, and T98G (GBM cell lines) and SVGp12 (normal human glial cell line) were obtained from the Bioresource Collection and Research Center (BCRC).

    Techniques: MTT Assay, Enzyme-linked Immunosorbent Assay